Partnering
Collaboration

Commercialization

From R&D to commercialization

Marketed in Korea (Licensed out to Daewoong) - Luphere® Depot

Luphere® Depot is licensed out and marketed as a generic product in Korea by Daewoong Pharmaceuticals and similar efficacy and safety were confirmed successfully compare with original product through Phase IV study in Korea.

Leuprolide, also known as leuprorelin, is a manufactured version of a hormone used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and early puberty. It is given by injection into a muscle or under the skin. Leuprolide is in the gonadotropin-releasing hormone (GnRH) analogue family of medication. It works by decreasing gonadotropin and therefore decreasing testosterone and estradiol.

When administered chronically at a higher dose, it paradoxically produces antagonistic inhibitory effects on pituitary gonadotropin secretion and testicular or ovarian steroidogenesis. These effects, attributable to down regulation of the receptors, are temporary and reversible.

It was a great and first experience from R&D to commercialization of SmartDepot technology and become a key foundation for upcoming product development.

BE Preparation - PT201 for Acromegaly

Octreotide is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. Octreotide can be used in the treatment of Acromegaly, a disorder of excessive growth hormone (GH). Octreotide, being a somatostatin analog, inhibits the release of GH from the pituitary gland through a process normally involved in negative feedback.

Peptron completed Pilot bioequivalence study in Canada for SR-Octreotide and currently, new formulation using PLGA-glucose is being optimized by animal study. Preliminary PK profile with similar Cmax and AUC was obtained compared with original one so additional PK animal study is ongoing to confirm optimization.

Currently, Peptron agreed with Penmix as a commercial manufacturing partner in global and looking for sale partners in their interested markets.Currently, Peptron agreed with Penmix as a commercial manufacturing partner in global and looking for sale partners in their interested markets.

Contact us

If you are interested in contacting Peptron regarding partnering opportunities, please email the Business Development Team at biz@peptron.com